Zhen Zhang Selected Research

Neoplasm Metastasis (Metastasis)

12/2023	Zuogui pill disrupt the malignant cycle in breast cancer bone metastasis through the Piezo1-Notch-1-GPX4 pathway and active molecules fishing.
11/2023	Preoperative prediction of cholangiocyte phenotype hepatocellular carcinoma on contrast-enhanced MRI and the prognostic implication after hepatectomy.
1/2023	Patient-derived tumor organoids predict responses to irinotecan-based neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer.
1/2023	Analysis of prognostic factors affecting immune checkpoint inhibitor therapy in tumor patients exposed to antibiotics.
1/2023	lncRNA BREA2 promotes metastasis by disrupting the WWP2-mediated ubiquitination of Notch1.
1/2023	RIFLE: a Phase II trial of stereotactic ablative radiotherapy combined with fruquintinib and tislelizumab in metastatic colorectal cancer.
12/2022	Knockdown RBM15 Inhibits Colorectal Cancer Cell Proliferation and Metastasis Via N6-Methyladenosine (m6A) Modification of MyD88 mRNA.
11/2022	Patient-Derived Organoids from Colorectal Cancer with Paired Liver Metastasis Reveal Tumor Heterogeneity and Predict Response to Chemotherapy.
10/2022	Genomic Instability in Cerebrospinal Fluid Cell-Free DNA Predicts Poor Prognosis in Solid Tumor Patients with Meningeal Metastasis.
3/2022	Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of locally advanced rectal cancer: a randomized, prospective, multicentre, double-arm, phase II trial (TORCH).

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Zhen Zhang Research Topics

Disease

457	Neoplasms (Cancer) 05/2024 - 08/2002
75	Inflammation (Inflammations) 05/2024 - 08/2004
73	Rectal Neoplasms (Rectal Cancer) 02/2024 - 12/2010
68	Infections 05/2024 - 12/2006
60	Breast Neoplasms (Breast Cancer) 02/2024 - 08/2002
58	Neoplasm Metastasis (Metastasis) 12/2023 - 02/2008
47	Stomach Neoplasms (Stomach Cancer) 12/2023 - 06/2012
36	Wounds and Injuries (Trauma) 02/2024 - 07/2007
36	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 04/2013
32	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 01/2015
32	Ovarian Neoplasms (Ovarian Cancer) 06/2023 - 11/2002
30	Glioma (Gliomas) 01/2024 - 08/2009
28	Lung Neoplasms (Lung Cancer) 04/2024 - 06/2011
27	Hypoxia (Hypoxemia) 03/2024 - 03/2007
25	Fibrosis (Cirrhosis) 05/2024 - 01/2015
24	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2023 - 08/2002
24	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2004
23	Pain (Aches) 04/2024 - 02/2010
22	Heart Failure 04/2024 - 01/2015
22	Esophageal Squamous Cell Carcinoma 03/2024 - 01/2012
22	Carcinoma (Carcinomatosis) 01/2022 - 08/2002
21	COVID-19 05/2024 - 01/2020
21	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 03/2012
21	Ischemic Stroke 12/2023 - 12/2014
20	Carcinogenesis 11/2023 - 03/2012
20	Type 2 Diabetes Mellitus (MODY) 10/2023 - 07/2012
19	Adenocarcinoma 12/2022 - 02/2004
18	Insulin Resistance 11/2023 - 01/2011
17	Colonic Neoplasms (Colon Cancer) 01/2024 - 01/2013
17	Myocardial Infarction 11/2023 - 01/2011
16	Melanoma (Melanoma, Malignant) 04/2024 - 01/2013
16	Body Weight (Weight, Body) 11/2023 - 07/2010
15	Esophageal Neoplasms (Esophageal Cancer) 03/2024 - 10/2004
15	Necrosis 01/2024 - 11/2002
14	Reperfusion Injury 04/2024 - 06/2013
14	Ischemia 05/2023 - 03/2007
14	Pancreatic Neoplasms (Pancreatic Cancer) 02/2022 - 02/2004
13	Neuroinflammatory Diseases 01/2024 - 01/2012
13	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 01/2017
12	Virus Diseases (Viral Diseases) 03/2024 - 09/2006
12	Obesity 03/2024 - 12/2016
12	Osteoporosis 12/2023 - 04/2010
12	Sepsis (Septicemia) 11/2023 - 04/2008
12	Stroke (Strokes) 11/2023 - 07/2003
12	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 03/2016
11	Glioblastoma (Glioblastoma Multiforme) 05/2024 - 02/2014
11	Osteosarcoma (Osteogenic Sarcoma) 05/2024 - 03/2015
11	Diabetes Mellitus 08/2023 - 05/2012

Drug/Important Bio-Agent (IBA)

145	Proteins (Proteins, Gene)FDA Link 04/2024 - 08/2002
113	Biomarkers (Surrogate Marker)IBA 05/2024 - 08/2002
40	CytokinesIBA 12/2023 - 06/2012
39	Messenger RNA (mRNA)IBA 03/2024 - 01/2006
36	MicroRNAs (MicroRNA)IBA 06/2023 - 02/2011
34	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 01/2011
33	RNA (Ribonucleic Acid)IBA 01/2024 - 01/2006
32	Therapeutic UsesIBA 04/2024 - 04/2007
29	Long Noncoding RNAIBA 12/2023 - 01/2017
28	VaccinesIBA 05/2024 - 07/2005
28	EnzymesIBA 01/2024 - 06/2007
25	Transcription Factors (Transcription Factor)IBA 10/2023 - 08/2006
24	AntigensIBA 03/2024 - 12/2002
23	DNA (Deoxyribonucleic Acid)IBA 04/2023 - 11/2002
21	LipidsIBA 05/2024 - 01/2011
21	Peptides (Polypeptides)IBA 04/2024 - 01/2011
20	Immune Checkpoint InhibitorsIBA 03/2024 - 01/2021
19	Triglycerides (Triacylglycerol)IBA 12/2023 - 04/2011
18	Interleukin-6 (Interleukin 6)IBA 04/2023 - 01/2011
17	CholesterolIBA 04/2024 - 01/2012
17	HydrogelsIBA 02/2024 - 01/2019
17	AntioxidantsIBA 01/2024 - 01/2012
17	Anti-Bacterial Agents (Antibiotics)IBA 10/2023 - 12/2009
16	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2024 - 01/2016
16	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2024 - 03/2007
15	Antiviral Agents (Antivirals)IBA 05/2024 - 04/2015
14	Indicators and Reagents (Reagents)IBA 08/2023 - 07/2011
14	LigandsIBA 01/2023 - 08/2012
14	Phosphotransferases (Kinase)IBA 11/2022 - 03/2015
14	Small Interfering RNA (siRNA)IBA 10/2022 - 06/2009
14	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 01/2012
13	CollagenIBA 01/2024 - 01/2009
13	InflammasomesIBA 01/2024 - 01/2019
13	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2023 - 01/2013
13	ProteomeIBA 05/2023 - 01/2015
12	NF-kappa B (NF-kB)IBA 04/2024 - 01/2011
12	Capecitabine (Xeloda)FDA Link 01/2024 - 01/2013
12	Insulin (Novolin)FDA Link 11/2023 - 01/2011
12	Cisplatin (Platino)FDA LinkGeneric 06/2023 - 11/2007
12	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2023 - 12/2009
11	Paclitaxel (Taxol)FDA LinkGeneric 02/2024 - 11/2009
11	Chimeric Antigen ReceptorsIBA 01/2024 - 10/2015
11	Fluorouracil (Carac)FDA LinkGeneric 01/2022 - 09/2011

Therapy/Procedure

196	Therapeutics 04/2024 - 10/2004
89	Radiotherapy 03/2024 - 03/2005
82	Drug Therapy (Chemotherapy) 04/2024 - 03/2005
64	Immunotherapy 05/2024 - 01/2006
49	Neoadjuvant Therapy 01/2024 - 10/2004
37	Chemoradiotherapy 03/2024 - 10/2004
19	Chinese Traditional Medicine (Traditional Chinese Medicine) 12/2023 - 10/2008
19	Lasers (Laser) 01/2023 - 02/2004
12	Photochemotherapy (Photodynamic Therapy) 12/2022 - 12/2009